微生物生态学和环境基因组学

开发和完善高通量宏基因组分子技术，包括高通量测序和基因芯片方法；应用这一新的分子技术研究地域地理差异、全球环境变化和污染等生态过程中微生物群落的响应和反馈机制，揭示微生物群落的组成、结构和功能多样性，物种间的相互作用以及群落与其所生存环境间的关联作用等。 

代表性研究项目：

（1）2023年-2026年，开发基于毒力基因的环境病原菌检测技术和风险评估方法, 国家自然科学基金面上项目, 项目负责人；

（2）2022年至2025年, 中国-沙特阿拉伯干旱区农业微生物联合实验室, 科技部国家重点研发计划, 课题负责人；

（3）2020年至2023年，黄河三角洲湿地生态系统中微生物驱动的碳氮元素循环过程和机制, 国家自然基金联合资助项目，项目负责人；

（4）2020年至2023年，城市有机固废生物转化功能菌群及其代谢网络调控的基础理论，科技部国家重点研发计划，课题负责人；

2018年至今连续7年入选科睿唯安全球高被引学者；获国家级项目领军人才、青年拔尖人才荣誉。

代表性论文

1. Xingsheng Yang; Xi Peng; Kai Feng; Shang Wang; Xiao Zou; Ye Deng. Organic molecular network analysis reveals transformation signatures of dissolved organic matter during anaerobic digestion process. Water Research, 2025, 10.1016/j.watres.2025.123777.

2. Kai Feng, Ye Deng. Intertwined Relationship Between Soil pH and Microbes in Biogeography. Global Change Biology, 2025, 31(4):e70208.

3. Xi Peng, Shang Wang, Miaoxiao Wang, Kai Feng, Qing He, Xingsheng Yang, Weiguo Hou, Fangru Li, Yuxiang Zhao, Baolan Hu, Xiao Zou, Ye Deng*. Metabolic interdependencies in thermophilic communities are revealed using co-occurrence and complementarity networks. Nature Communications, 2024, 15: 8166.

4. Xingsheng Yang, Kai Feng, Shang Wang, Mengting Maggie Yuan, Xi Peng, Qing He, Danrui Wang, Wenli Shen, Bo Zhao, Xiongfeng Du, Yingcheng Wang, Linlin Wang, Dong Cao, Wenzong Liu, Jianjun Wang, Ye Deng* . Unveiling the deterministic dynamics of microbial meta-metabolism: a multi-omics investigation of anaerobic biodegradation. Microbiome, 2024, 12: 166.

5. Kai Feng, Shang Wang, Qing He, Michael Bonkowski, Mohammad Bahram, Etienne Yergeau, Zhujun Wang, Xi Peng, Danrui Wang, Shuzhen Li, Yingcheng Wang, Zhicheng Ju, Xiongfeng Du, Chengliang Yan, Songsong Gu, Tong Li, Xingsheng Yang, Wenli Shen, Ziyan Wei, Qiulong Hu, Pengfei Li, Yanmei Zhu, Guangxin Lu, Clara Qin, Gengxin Zhang, Chunwang Xiao, Yunfeng Yang, Jizhong Zhou, Ye Deng*. CoBacFM: Core Bacteria Forecast Model for Global Grassland pH Dynamics under Future Climate Warming Scenarios. One Earth, 2024, 7(7): 1275-1287.

6. Tong Li, Kai Feng, Shang Wang, Xingsheng Yang, Xi Peng, Qichao Tu, Ye Deng*. Beyond Water and Soil: Air Emerges as a Major Reservoir of Human Pathogens. Environment International, 2024, 190: 108869.

7. Qing He, Shang Wang*, Kai Feng, Sean T Michaletz, Weiguo Hou, Wenhui Zhang, Fangru Li, Yidi Zhang, Danrui Wang, Xi Peng, Xingsheng Yang, Ye Deng*. High speciation rate of niche specialists in hot springs. The ISME Journal, 2023, doi.org/10.1038/s41396-023-01447-4.

8. Danrui Wang, Jiangtao Li, Lei Su, Wenli Shen, Kai Feng, Xi Peng, Zhujun Wang, Bo Zhao, Zheng Zhang, Zhaojing Zhang, Étienne Yergeau, Ye Deng. Phylogenetic diversity of functional genes in deep-sea cold seeps: a novel perspective on metagenomics. Microbiome, 2023, 11: 276.

9. Zheng Zhang, Jiang Li*, Hongjun Li, Linlin Wang, Yuqi Zhou, Shuzhen Li, Zhaojing Zhang, Kai Feng, Ye Deng*. Environmental DNA metabarcoding reveals the influence of human activities on microeukaryotic plankton along the Chinese coastline. Water Research, 2023, 233: 119730

10. Lingzhan Miao, Wanyi Li, Tanveer M. Adyel, Yu Yao, Ye Deng*, Jun Wu, Yongqiang Zhou, Yue Yu, Jun Hou*. Spatio-temporal succession of microbial communities in plastisphere and their potentials for plastic degradation in freshwater ecosystems. Water Research, 2023, doi.org/10.1016/j.watres.2022.119406.

11. Yuqi Zhou, Baoyu Sun, Baohua Xie, Kai Feng, Zhaojing Zhang, Zheng Zhang, Shuzhen Li, Xiongfeng Du, Qi Zhang, Songsong Gu, Wen Song, Linlin Wang, Jianyang Xia, Guangxuan Han*, Ye Deng*. Warming reshaped the microbial hierarchical interactions. Global Change Biology, 2021. doi.org/10.1111/gcb.15891.

12. Ziyan Wei, Kai Feng, Zhujun Wang, Yu Zhang, Min Yang, Yong-Guan Zhu, Marko P. J. Virta, and Ye Deng*. High-Throughput Single-Cell Technology Reveals the Contribution of Horizontal Gene Transfer to Typical Antibiotic Resistance Gene Dissemination in Wastewater Treatment Plants. Environmental Science & Technology, 2021, DOI: 10.1021/acs.est.1c01250.

13. Shang Wang#, Xuelian Bao#, Kai Feng#, Ye Deng*, Wenjun Zhou, Pengshuai Shao, Tiantian Zheng, Fei Yao, Shan Yang, Shengen Liu, Rongjiu Shi, Zhen Bai, Hongtu Xie, Jinghua Yu, Ying Zhang, Yiping Zhang, Liqing Sha, Qinghai Song, Yuntong Liu, Jizhong Zhou, Yuguang Zhang, Hui Li, Qingkui Wang, Xingguo Han, Yongguan Zhu, Chao Liang*. Warming-driven migration of core microbiota projects soil property changes at continental scale. Science Bulletin, 2021, 10.1016/j.scib.2021.01.021.

14. Zhujun Wang#, Guangxin Lu#, Mengting Yuan, Hao Yu, Shang Wang, Xin Li, Ye Deng*. Elevated temperature overrides the effects of N amendment in Tibetan grassland on soil microbiome. Soil Biology and Biochemistry, 2019, 136: 107532.

15. Huayu Qin, Shang Wang, Kai Feng, Zhili He, Marko P. J. Virta, Weiguo Hou, Hailiang Dong, Ye Deng*. Unraveling the diversity of sedimentary sulfate-reducing prokaryotes (SRP) across Tibetan saline lakes using epicPCR. Microbiome, 2019, 7:71.

16. Ziyan Wei, Yueni Wu, Kai Feng, Min Yang, Yu Zhang, Qichao Tu, Jun Wang, Ye Deng*. ARGA, a pipeline for primer evaluation on antibiotic resistance genes. Environment International, 2019, 128:137-145.

17. Zhaojing Zhang, Ye Deng*, Kai Feng, Weiwei Cai, Shuzhen Li, Huaqun Yin, Meiying Xu, Daliang Ning, Yuanyuan Qu*. Deterministic assembly and diversity gradient altered the biofilm community performances of bioreactors. Environmental Science & Technology, 2019, 53(3): 1315-1324.